Fabio E. S. Souza,Bahareh Khalili,Annyt Bhattacharyya
申请号:
US16139352
公开号:
US10487059B2
申请日:
2018.09.24
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention provides a novel crystalline form of Eluxadoline, Eluxadoline Form APO-I, a co-crystal of Eluxadoline and methyl nicotinate, compositions and processes for the preparation thereof, and the use of this crystalline form in the treatment of opioid-modulated disorders, and in particular, gastrointestinal disorders, including irritable bowel syndrome with diarrhea (IBS-D).