HAI WU,Sheng YAO,Yuehua ZHOU,Jian YAO,Dan MENG,Hui FENG
申请号：
US16487035
公开号：
US20190367618A1
申请日:
2018.02.13
申请国别(地区):
US
年份:
2019
代理人:
摘要：
An antibody or a functional fragment thereof that specifically bind to PD-L1 with high affinity, a nucleic acid molecule that encodes said antibody or the functional fragment thereof, an expression vector and a host cell for use in expressing said antibody or the functional fragment thereof, and a method for producing said antibody or the functional fragment thereof. An immunoconjugate and a pharmaceutical composition containing said antibody or the functional fragment thereof, and a method for using said antibody or the functional fragment thereof to enhance the function of a T cell so as to up-regulate a cell-mediated immune response, for use in treating diseases caused by T cell dysfunction.
