PHARMACEUTICAL COMBINATIONS OF AN ANGIOTENSIN RECEPTOR ANTAGONIST AND AN NEP INHIBITOR

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专利权人:

发明人:

펭, 릴리,고트프레드센, 스벤, 에릭,카핀스키, 피오트르,서튼, 폴, 알렌,프라샤드, 마하비르,기르기스, 마이클, 제이.,휴, 빈,리우, 유강,블랙록, 토마스, 제이.

申请号：

KR1020077015021

公开号：

KR1014328210000B1

申请日:

2006.11.08

申请国别(地区):

KR

年份:

2014

代理人:

摘要：

The invention relates to a dual-acting compound having the sum formula [(( S )- N -valeryl- N- {[2'-(1 H -tetrazole-5-yl)-biphenyl-4-yl]-methyl}-valine) ((2 R ,4 S )-5-biphenyl4-yl-5-(3-carboxy-propionylamino)-2-methyl-pentanoic acid ethyl ester)]Na1-3 x H2O, wherein x is 0 to 3, and related invention embodiments. The dual-acting compound is an angiotensin receptor blocker and a neutral endopeptidase inhibitor.안지오텐신 수용체 길항제 및 NEPi의 특정 조합물, 연결된 프로드러그 또는 화합물은 고혈압의 치료에 사용된다.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/