The present invention relates to novel compounds of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use of these compounds in medicine and the intermediates involved in their preparation. The inventors have found that compounds of general formula (I) inhibit HIF hydroxylases, thereby increasing the stability and/or reactivity of hypoxia inducible factor (HIF). They therefore have utility in any disease state where ischemia, hypoxia and/or anemia plays a role.
