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DRUG CONJUGATE COMPOSITION
专利权人:
ImmunoGen; Inc.
发明人:
Godfrey AMPHLETT,Wei ZHANG,Michael FLEMING,Hung-Wei CHIH
申请号:
US15159211
公开号:
US20160367696A1
申请日:
2016.05.19
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention provides a liquid composition and a lyophilized composition comprising a therapeutically effective amount of a conjugate comprising an antibody chemically coupled to a maytansinoid. The invention further provides a method for killing a cell in a human comprising administering to the human either of the compositions such that the antibody binds to the surface of the cell and the cytotoxicity of the maytansinoid is activated, whereby the cell is killed.
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