Randy Lee Webb;Friedrich Cameron LUFT;Dominik Nicolas Mueller;David Louis FELDMAN
发明人:
David Louis FELDMAN,Friedrich Cameron LUFT,Dominik Nicolas Mueller,Randy Lee Webb
申请号:
US13709549
公开号:
US20130196977A1
申请日:
2012.12.10
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention provides methods for the prevention of, delay progression to overt to, or the treatment of diastolic dysfunction or diastolic heart failure which method comprises administering to a warm-blooded animal a therapeutically effective amount of a renin inhibitor, or a pharmaceutically acceptable salt thereof, alone or in combination with(i) an ACE inhibitor or a pharmaceutically acceptable salt thereof; or(II) an angiotensin II receptor blocker or a pharmaceutically acceptable salt thereof.