YUNG-CHIEH TSENG;CHI-HUEY WONG;ACADEMIA SINICA;CHE MA
发明人:
CHI-HUEY WONG,CHE MA,YUNG-CHIEH TSENG
申请号：
IL22614313
公开号：
IL226143A
申请日:
2013.05.02
申请国别(地区):
IL
年份:
2020
代理人:
摘要：
Methods for producing virus particles with simplified glycosylation on structural or surface proteins, such as mono-glycosylated forms of influenza A virus, NIBRG-14 (H5N1). When used as targets for vaccine production, the conserved nature of such sites generates vaccines that are less sensitive to viral mutations. Such methods may include the use of glycosylation inhibitors for production of viruses with simplified glycosylation profiles.
