Immunogenic compositions and methods of use

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专利权人:

アーティフィシャル セル テクノロジーズ インコーポレイテッド

发明人:

ヘイニー ドナルド テンプルトン

申请号：

JP2008537917

公开号：

JP5751741B2

申请日:

2006.10.25

申请国别(地区):

JP

年份:

2015

代理人:

摘要：

Disclosed herein are immunogenic compositions comprising a multilayer film comprising two or more layers of polyelectrolytes, wherein adjacent layers comprise oppositely charged polyelectrolytes. A first layer polyelectrolyte comprises an antigenic polypeptide comprising one or more surface adsorption regions covalently linked to one or more antigenic determinant regions, wherein the antigenic polypeptide and the one or more surface adsorption regions have the same polarity. The immunogenic compositions may be employed in methods of eliciting an immune response in a vertebrate organism.

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