Nucleic acid with anti-metabolic syndrome effect

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专利权人:

国立大学法人北海道大学;塩野義製薬株式会社

发明人:

光武 進,座間 宏太,五十嵐 靖之,吉田 哲也,田中 嘉一,武本 浩

申请号：

JP2013511193

公开号：

JP5860038B2

申请日:

2011.09.21

申请国别(地区):

JP

年份:

2016

代理人:

摘要：

The problem of the present invention is to prove a medicament for decreasing body weigh, a medicament for decreasing visceral fat, a medicament for decreasing triglyceride in the liver, and a method for screening a medicament for ameliorating obesity and fatty liver. The problem is solved by a method comprising measuring an activity of a candidate material for inhibiting a sphingomyelin synthetase wherein if the candidate material has an activity for inhibiting a sphingomyelin synthetase, the candidate material is judged to have at least one function selected from the consisting of an anti-obesity drug, a drug for decreasing visceral fat, a drug for treating fatty liver and an agent for increasing adiponectin expression.

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中国工程科技知识中心

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