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METABOLITES DE DERIVES DE (THIO)CARBAMOYLCYCLOHEXANE
专利权人:
RICHTER GEDEON NYRT.
发明人:
AGAINE CSONGOR, EVA,KIRSCHNER, NORBERT ANTAL,SCHMIDT, EVA,GYERTYAN, ISTVAN,KISS, BELA
申请号:
CA2684149
公开号:
CA2684149C
申请日:
2008.05.15
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention relates to metabolites of (thio)-carbamoylcyclohexane derivatives, particularly, metabolites oftrans-4-{2-[4-(2,3-dichlorophenyl)-piperazin-1-yl]-ethyl}-N,N-dimethylcarbamoyl-cyclohexylamine andpharmaceutically acceptable salts thereof, to pharmaceutical compositionscontainingthe same and to their use in the treatment and/or prevention of a conditionswhichrequires, modulation of dopamine receptors. The compounds of the presentinventionhave the general formula (IIa):(see formula IIa)Preferably R1 and R2 are both H or CH3, or one is H and the other CH3.
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