PARK, KI DUKKR,박기덕,PAE, AE NIMKR,배애님,PARK, JONG HYUNKR,박종현,CHOI, JI WONKR,최지원,KIM, DONG JINKR,김동진,KIM, YUN KYUNGKR,김윤경
申请号：
KR1020150190890
公开号：
KR1017121840000B1
申请日:
2015.12.31
申请国别(地区):
KR
年份:
2017
代理人:
摘要：
The present invention relates to a sesquiterpene compound which is derived from natural substances and is involved in the activation of nuclear factor erythroid 2-related factor 2 (Nrf2), thereby showing pharmaceutical activities on ophthalmoneuromyelitis or inhibition of nerve cell death. The present invention further relates to a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing the compounds as an active ingredient.COPYRIGHT KIPO 2017본 발명은 NF-E2-related factor-2(Nrf2) 활성에 작용하여 신경세포 사멸 억제 또는 시신경 척수염 질환에 약학적 활성을 보이는 천연물 유래의 세스퀴터핀 화합물 및 이의 약제학적으로 허용가능한 염, 그리고 이들 화합물을 유효성분으로 함유하는 약학조성물에 관한 것이다.
