A composition for the topical application on a mammalian skin comprises one or more Brassica plant extracts selected from the group consisting of: extract extract Brassica oleracea botrytis extract and extract. The composition further comprises one or more selected from the group consisting of:extract curcuminoids tetrahydrocurcuminoids metabolites of curcuminoids or tetrahydrocurcuminoids and derivatives of curcuminoids or tetrahydrocurcuminoids. The composition further comprises one or more selected from the group consisting of: extract extract green tea extract and white tea extract Wasabia japonica extract extract extract and one or both of extract or tetrahydropiperine.