Targeting compounds and methods for their production

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专利权人:

The University of Melbourne

发明人:

DONNELLY, Paul Stephen,ZIA, Nicholas Alan

申请号：

AU2019251767

公开号：

AU2019251767A1

申请日:

2019.04.11

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

The present invention is directed to sarcophagine based compounds of formula (I). The compounds can complex a radioisotope, such as 64-copper and hence are useful in radioimaging and radiotherapy of cancers, e.g. colorectal cancer. The compounds work via a pre-targeting imaging approach in which the tetrazine reacts via click chemistry with a functional group such as a trans- cyclooctene which is pre-bound to a ligand such as a tumour specific antibody.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/