PSEUDOMONAS EXOTOXIN A CD4+ T-CELL EPITOPES

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专利权人:

Cambridge Antibody Technology Limited

发明人:

Harding, Fiona Anne

申请号：

AU2013200665

公开号：

AU2013200665A1

申请日:

2013.02.06

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

#$%^&*AU2013200665A120130228.pdf#####ABSTRACT The present invention provides PE CD+ T-cell epitopes, as well as novel variants that exhibit reduced immunogenic responses, as compared to the parental PE. The present invention 5 further provides DNA molecules that encode novel PE variants, host cells comprising DNA encoding novel PE variants, as well as methods for making PEs less immunogenic. In addition, the present invention provides various compositions that comprise these PE variants that are less immunogenic than wild-type PEs.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/