抗体を成分として含む医薬品の有効性の判定方法
- 专利权人:
- 发明人:
- 申请号：
- JP20120533838
- 公开号：
- JP5682976(B2)
- 申请日:
- 2011.08.26
- 申请国别(地区):
- 日本
- 年份:
- 2015
- 代理人:
- 摘要：
Provided is a method for determining effectiveness of medicine containing, as components, antibodies that are active components of an antibody preparation such as trastuzumab, or antibodies for a target to a target site of active component, by determining the quantity of the protein recognized by the antibodies with high accuracy, in a quantitative tissue staining method for biological tissue. The effectiveness of the medicine containing antibodies as components is determined by using the tissue staining method including the following steps: a step of labeling the antibodies in a medicine that contains antibodies as components with a fluorescent substance, and bringing the fluorescently labeled antibodies into contact with a tissue sample; a step of irradiating the tissue site contacted with the antibodies with excitation light to obtain a fluorescence image; a step of obtaining an intrinsic fluorescence image in the vicinity of the short-wavelength side or long-wavelength side of the acquisition area of f
- 来源网站：
- 中国工程科技知识中心
