Panitch, Alyssa,Paderi, John Eric,Park, Kinam,Stuart, Katherine,Higbee, Steve
申请号:
HRP20190691
公开号:
HRP20190691T1
申请日:
2019.04.12
申请国别(地区):
HR
年份:
2019
代理人:
摘要:
This invention relates to collagen-binding synthetic peptidoglycans and engineered collagen matrices comprising a collagen matrix and a collagen-binding synthetic peptidoglycan where the collagen-binding synthetic peptidoglycan can be aberrant or can have amino acid homology with a portion of the amino acid sequence of a protein or a proteoglycan that regulates collagen fibrillogenesis. The invention also relates to kits, compounds, compositions, and engineered graft constructs comprising such collagen-binding synthetic peptidoglycans or engineered collagen matrices and methods for their preparation and use.