Use of an ion exchange membrane to remove impurities from cell-binding agent cytotoxic agent conjugates

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专利权人:

ImmunoGen; Inc.

发明人:

Li, Xinfang,Cheng, Wenjie

申请号：

AU2013326897

公开号：

AU2013326897A1

申请日:

2013.10.04

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

The invention provides processes for preparing purified cell-binding agent cytotoxic agent conjugates comprising subjecting a mixture comprising a cell-binding agent cytotoxic agent conjugate and one or more impurities to an ion exchange chromatography membrane to remove at least a portion of the impurities from the mixture, thereby providing a purified cell-binding agent cytotoxic agent conjugate.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/