Arrangement to detect fatigue and assess the effectiveness of means to mitigate that fatigue, through use of naps, caffeine and water etc. Fatigue information is received for a subject and determination is made as to whether the subject is fatigued. In an instance in which the subject is fatigued, the method determines an estimated effectiveness of each of a plurality of fatigue mitigation strategies based upon fatigue information for the subject and at least one of a time to become effective, a duration of the effectiveness and a side effect. The method also selects at least one fatigue mitigation strategy to address fatigue of the subject.
