KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY;한국화학연구원
发明人:
KIM PILHO,김필호,KIM HYOUNG RAE,김형래,YUN CHANG SOO,윤창수,CHO SUNG YUN,조성윤,HWANG JONG YEON,황종연,HA JAE DU,하재두,JUNG HEE JUNG,정희정,MATHI G.R.,마티지알
申请号:
KR1020190103072
公开号:
KR1020190101937A
申请日:
2019.08.22
申请国别(地区):
KR
年份:
2019
代理人:
摘要:
In one aspect of the present invention, provided are amatoxin derivatives, methods for preparing the same, synthetic intermediates of amatoxin derivatives, and a pharmaceutical composition for the treatment of cancer including amatoxin derivatives. Provided in the present invention are a compound represented by formula (I), an optical isomer thereof, or a pharmaceutically acceptable salt thereof.COPYRIGHT KIPO 2020본 발명의 일 측면에 있어서, 아마톡신 유도체, 이의 제조방법, 아마톡신 유도체의 합성 중간체, 아마톡신 유도체를 포함하는 암 치료용 약학적 조성물이 제공된다.