Pirimidinona substituted Compounds, Pharmaceutical composition that comprises； their use to treat Alzheimer's disease and Atherosclerosis.

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专利权人:

GLAXO GROUP LIMITED

发明人:

JIN YUN,WAN ZEHONG,ZHANG QING

申请号：

CL2013001604

公开号：

CL2013001604A1

申请日:

2013.06.05

申请国别(地区):

CL

年份:

2014

代理人:

摘要：

The present invention relates to novel compounds that inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease, and/or diabetic macular edema.COMPUESTOS DERIVADOS DE PIRIMIDINONA SUSTITUIDA, INHIBIDORES DE LA FOSFOLIPASA ASOCIADA CON LIPOPROTEINAS A2 (LP-PLA2)； COMPOSICION FARMACEUTICA QUE LOS COMPRENDE； UTILES PARA TRATAR LA ENFERMEDAD DE ALZHEIMER Y LA ATEROSCLEROSIS.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/