Holger Wagner,Daniela Berta,Klaus Fuchs,Riccardo Giovannini,Dieter Wolfgang Hamprecht,Ingo Konetzki,Ruediger Streicher,Thomas Trieselmann
申请号:
US13397855
公开号:
US20130053404A1
申请日:
2012.02.16
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to compounds defined by formula Iwherein the variables R1-R8 are defined as in the description, possessing valuable pharmacological activity. Particularly, the compounds are inhibitors of cholesterol ester transfer protein (CETP) and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme.