Research Foundation of the City University of New York
发明人:
Robert R. Alfano,Yang Pu,Lingyan Shi,Sebastião Pratavieira
申请号：
US14299564
公开号：
US20140371582A1
申请日:
2014.06.09
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A method is provided for deep tissue imaging using multi-photon excitation of a fluorescent agent. The fluorescent agent is irradiated with an ultrafast laser to produce an excited singlet state (Sn) which subsequently undergoes non-radiative relaxation to a first singlet state (S1). The S1 state undergoes fluorescence to the ground state S0 to produce an emission wavelength. Both the excitation and emission wavelengths are within the near infrared optical window, thereby permitting deep tissue penetration for both the incoming and outgoing signals.
