Oliver Plettenburg;John Weston;Matthias Loehn;Olivier Duclos;Heinz-Werner Kleemann;Frederic Jeannot;Katrin Lorenz
发明人:
Oliver Plettenburg,Katrin Lorenz,John Weston,Matthias Loehn,Heinz-Werner Kleemann,Olivier Duclos,Frederic Jeannot
申请号:
US13000754
公开号:
US08541449B2
申请日:
2009.06.19
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The invention relates to substituted isoquinoline and isoquinolinones of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.