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Cell adhesion inhibitor, cell growth inhibitor, and cancer test method and test kit
专利权人:
国立大学法人;宮崎大学
发明人:
森下 和広,齋藤 祐介
申请号:
JP2013515140
公开号:
JP6029019B2
申请日:
2012.05.11
申请国别(地区):
JP
年份:
2016
代理人:
摘要:
PROBLEM The object is to provide a prevention/treatment means for cancer, by controlling expression/function of a target molecule different from a conventional one, as a novel method in the molecularly-targeted treatment method for a cancer. In addition, provided is a screening means for a substance having prevention/treatment activity for a cancer, using the above target molecule. Moreover, provided is a simple and rapid means for examining a cancer using the detection of the above target molecule. SOLUTION According to one aspect of the present invention, there is provided a cell proliferation inhibitor or a cell adhesion inhibitor for a cancer cell, containing an antibody to a protein containing the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID No: 2 or a partial peptide thereof. According to another aspect of the present invention, there is provided a cell adhesion inhibitor for a cancer cell, containing an antisense polynucleotide containing a complementary or substantially complementary base sequence to a base sequence of a polynucleotide encoding a protein containing the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID No: 2 or a part thereof. According to further another aspect of the present invention, there is provided a cell adhesion inhibitor for a cancer cell, containing a substance to inhibit expression and/or activity of protein containing the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID No: 2. According to further another aspect of the present invention, there is provided a method for examining a cancer including a step of detecting a protein containing the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID No: 2 or a partial peptide thereof, or a polynucleotide encoding a protein containing the same or substantially the same amino acid sequence
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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