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MARQUEURS BIOLOGIQUES A BASE DE CYTOKINE COMME MARQUEURS BIOLOGIQUES PREDICTIFS DE LA REPONSE CLINIQUE POUR L'ACETATE DE GLATIRAMERE
专利权人:
TEVA PHARMACEUTICAL INDUSTRIES LTD
发明人:
KASPER, LLOYD H.,SMITH, JACQUELINE Y.
申请号:
CA2814500
公开号:
CA2814500A1
申请日:
2011.10.10
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
A method for treating a human subject afflicted with multiple sclerosis or a single clinical attack consistent with multiple sclerosis with a pharmaceutical composition comprising glatiramer acetate and a pharmaceutically acceptable carrier, comprising the steps of determining whether the human subject is a glatiramer acetate responder by evaluating a biomarker selected from the group consisting of IL-17 concentration, TNF-a concentration, IL-2 concentration and IFN-? concentration, or a combination thereof, in the blood of the human subject and administering the pharmaceutical composition comprising glatiramer acetate and a pharmaceutically acceptable carrier to the human subject only if the human subject is identified as a glatiramer acetate responder.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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