There is provided thus wherein by with one or more mammalian target of rapamycin (mTOR) inhibitor (such as everolimus, ridaforolimus, and temsirolimu) combination management eribulin (such as eribulin mesylate, that is E7389, Halaven) for treating cancer (such as breast cancer, lung cancer, cancer of pancreas, primitive neuroectodermal tumors, lung cancer, oophoroma, carcinoma of endometrium, pharynx cancer, the cancer of the esophagus in a main body (such as a human patient) in needs, and sarcoma) method and external member.