#$%^&*AU2016238909A120161027.pdf#####PHARMACEUTICAL CREAM COMPOSITIONS COMPRISING OXYMETAZOLINE Abstract: Mozist Dry Irritate App Over Absorp_______________ Ease oTrial_20 ---------- --------- -I ~ra2 Elegant W Trial11 oily Trial 2 a Trial 36 ---- ------------------------------ -Color Ap - - ------------------ - -FI , App --------------------------- ---------------------- t-~---- FIG 1 0 2 4 8 Embodiments relating to cream formulations as well as oxymetazoline creams and methods for treating rosacea and symptoms associated with rosacea, including, for example, papules, pustules, phymas (skin thickening), telangiectasias or erythema associated with rosacea, other skin erythemas, telangiectasias, purpura or the like, and other manifestations associated therewith； other inflammatory conditions of the skin including, but not limited to, keratosis pilaris, lupus miliaris dissemniatus faciei, eczema, dermatitis, such as contact dermatitis, atopic dermatitis, seborrheic dermatitis, nummular dermatitis, generalized exfoliative dermatitis, statis dermatitis, neurodermatitis, lichen simplex chronicus, xerosis and xerotic dermatitis, dyshidrosis and dyshidrotic dermatitis, asteototic dermatitis or other conditions characterized by sensitive skin or a disturbance of the epidermal barrier； disorders characterized by rough, dry, cracked or fissured skin, disorders characterized by hyperkeratotic skin such as keratodermas and ichthyosisis and ichthyosiform dermatoses； disorders of hair follicles and sebaceous glands, such as acne, perioral dermatitis, and pseudofolliculitis barbae； disorders of sweat glands, such as miliaria, including, but not limited to, miliaria crystallina, miliaria rubra, miliaria profunda, miliaria pustulosa； sunburn, chronic actinic damage, poikiloderma, radiation dermatitis, actinic purpura ("solar purpura")； other inflammatory dermatoses, reactions and conditions of the skin, including, but n
