無定形レボノルゲストレル、固体分散体及びそれらの製造方法

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专利权人:

あすか製薬株式会社

发明人:

岩下 茂樹,林 博之,中川 隆義,宮崎 宏一

申请号：

JP20140561677

公开号：

JP6125547(B2)

申请日:

2014.04.23

申请国别(地区):

日本

年份:

2017

代理人:

摘要：

Provided are a new form of levonorgestrel, which is useful as an emergency contraception, etc., a solid dispersion of levonorgestrel, a manufacturing method for the same, and a drug composition.　The differential scanning calorimetry spectrum of this amorphous levonorgestrel has an exothermic peak at 51-61℃. This solid dispersion contains levonorgestrel dispersed in an amorphous state in a polymer. Said polymer may be a pharmaceutically acceptable water-soluble polymer. The weight ratio of the polymer to the levonorgestrel may be, in terms of polymer/levonorgestrel, 90/10-50/50.

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中国工程科技知识中心

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http://www.ckcest.cn/home/