Multimeric T-cell modulatory polypeptides and methods of use thereof

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专利权人:

Cue Biopharma; Inc.

发明人:

SEIDEL III, Ronald D.,CHAPARRO, Rodolfo J.

申请号：

AU2018328280

公开号：

AU2018328280A1

申请日:

2018.09.06

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

The present disclosure provides T-cell modulatory multimeric polypeptides that comprise an immunomodulatory polypeptide that exhibits reduced binding affinity to a cognate co-immunomodulatory polypeptide. A T-cell modulatory multimeric polypeptide is useful for modulating the activity of a T cell, and for modulating an immune response in an individual.

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中国工程科技知识中心

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