First and second image obtaining units respectively obtain a plurality of first projection images and a plurality of second projection images by tomosynthesis imaging operations according to first and second imaging conditions. A reconstructing unit reconstructs the plurality of first and second projection images employing processes of a reconstruction process that includes a filtering process other than the filtering process, to generate a plurality of first tomographic images and a plurality of second tomographic images for each of a plurality of cross sectional planes within a subject. A subtraction processing unit generates tomographic subtraction images from the first and second tomographic images. A filtering processing unit administers filtering processes on the tomographic subtraction images, to generate processed tomographic subtraction images.