The compounds of the formula (1) may be used to treat High Blood Pressure (e.g., pregnancy induced hypertension, preeclampsia, or pregnancy induced renal disease.Claim 1: a compound of the formula (1) or a pharmaceutically acceptable Salt thereof: aa¹ ARG Val - - - - - - his aa⁴ aa⁵ pro aa⁸ - o (1),Where aa¹ is a group consisting of amino acid residue seleccionadodel sarcosine and (2S, 3R, 4R, 5R) - 2,3,4,56 - pentahidroxilhexil) glycine aa⁴ is an amino acid residue selected from the group consisting of tyrosine or meta tyrosineEach of which is optionally substituted with at least one Substituent selected from the group consisting of Halo and hydroxyl or amino acid residue aa⁵ is selected from the group that builtIste in Valine, Leucine, isoleucine, Glycine, alanine, phenylalanine, threonine, Lysine and tyrosineEach of which is optionally substituted with at least one Substituent selected from the group consisting of c₁₋₆ c₄₋₆ alkyl, cycloalkyl, nh₂,Aryl and heteroaryl residue and aa⁸ is an amino acid selected from the group consisting of 1 - naftilalanina,(3 benzotienil) alanine and phenylalanine substituted with at least one Substituent selected from the group consisting of c₁₋₆ c₁₋₆ haloalquilo alkyl, cycloalkyl, c₄₋₆, Halo NS,Aryl and heteroaryl, in which at least one Substituent in the 2 position in the phenyl Ring of phenylalanine is an amino acid residue where aa⁸ D, and each aa⁴, ARG, Val, aa⁵,His and Pro in the formula (1) is a l amino acid residue.Los compuestos de la fórmula (1) podrán utilizarse para tratar la hipertensión (por ej., hipertensión inducida por el embarazo), preeclampsia o una enfermedad renal inducida por el embarazo. Reivindicación 1: Un compuesto de la fórmula (1), o una sal farmacéuticamente aceptable del mismo: AA¹-Arg-Val-AA⁴-AA⁵-His-Pro-AA⁸-OH (1), donde AA¹ es un residuo aminoácido seleccionadodel grupo que consiste de sarcosina y ((2S,3R,4R,5R)-2,3,4,5,6-pentahidroxilhexil)glicina AA⁴ es un residuo aminoácido seleccionado del grupo
