METHODS FOR OVERCOMING GLUCOCORTICOID RESISTANCE AND FOR DETERMINING GLUCOCORTICOID RESISTANCE POTENTIAL IN CANCER

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专利权人:

St. Jude Children's Research Hospital; Inc.

发明人:

Steven W. Paugh,William E. Evans,Erik Bonten

申请号：

US16590588

公开号：

US20200102565A1

申请日:

2019.10.02

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The invention provides methods for overcoming glucocorticoid resistance of cancers by inhibition of CASP1. Also disclosed are diagnostic methods for determining glucocorticoid resistance potential by measuring expression level or promoter methylation status of CASP1 gene and/or NLRP3 gene.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/