Polymorphic forms of Afatinib free base and Afatinib dimaleate

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专利权人:

Fresenius Kabi Oncology Ltd.

发明人:

Cabri, Walter,Lahiri, Saswata,Mishra, Bhuwan Bhaskar,Azim, Abul,Panda, Nilendu,Bhavanam, Poli Reddy,Ray, Krishanu,Kachhadia, Nikunj,Singh, Kumber

申请号：

AU2016276426

公开号：

AU2016276426A1

申请日:

2016.06.10

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

The present invention relates to crystalline forms of Afatinib and its dimaleate salt. The present invention also relates to processes for the preparation of crystalline forms of Afatinib and its dimaleate salt. The present invention further relates to pharmaceutical compositions of such crystalline forms of Afatinib dimaleate and use thereof in the treatment of a patient in need thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/