To provide a breath analysis device which minimizes mixing of gases between one portion of a breath and another portion of the breath.SOLUTION: In particular for example, when sampling and analyzing an end-tidal portion of an exhaled gas, a system disclosed herein may avoid mixing that can occur inside a device between an end-tidal sample and gases before and after the end-tidal sample. The system accomplishes this with a flow channel having an ultra-low uniform cross section and comprising componentry with ultra-low dead space.SELECTED DRAWING: Figure 9