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SONDE MOLÉCULAIRE POUR L'IMAGERIE DES ILÔTS DE LANGERHANS ET SON UTILISATION
专利权人:
Arkray, Inc.;Kyoto University
发明人:
申请号:
EP10813687.0
公开号:
EP2474326A1
申请日:
2010.08.31
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
To provide a molecular probe for imaging of pancreatic islets. A molecular probe for use in imaging of pancreatic islets is provided. The molecular probe includes any one of the following polypeptides: polypeptides represented by the following formulae (1), (5), and (9); and polypeptides having homology with the foregoing polypeptides:Z-DLSXQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2 (1)Z-DLSKQMEEEAVRLFIEWLXNGGPSSGAPPPS-NH2 (5)B-DLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2 (9)where X in the formulae (1) and (5) and B- in the formula (9) indicate that an amino group is labeled with a group represented by the formula (I) below having an aromatic ring,where A represents either an aromatic hydrocarbon group or an aromatic heterocyclic group, R1 represents a substituent that contains radioactive iodine, R2 represents either a hydrogen atom or a substituent different from that represented by R1, and R3 represents any one of a bond, a methylene group, and an oxymethylene group.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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