MODULATEURS DE KINASE DE TYPE RECEPTEUR ET PROCEDES D'UTILISATION

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专利权人:

Symphony Evolution; Inc.

发明人:

申请号：

EP03764599.1

公开号：

EP1521747B1

申请日:

2003.07.14

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention provides compounds which can modulate receptor kinase activity, particularly ephrin and EGFR, pharmaceutical compositions thereof and such compounds for use in treating cancer. The compounds comprise N-(3,4-dichloro-2-fluorophenyl)-7-({[(3aR,5r,6aS)-2-methyloctahydrocyclopenta [c]pyrrol-5-yl]methyl}oxy)-6-(methyloxy)quinazolin-4-amine and N-(3,4-dichloro-2-fluorophenyl)-7-({[(3aR,5s,6aS)-2-methyloctahydrocyclopenta[c]pyrrol-5-yl]methyl}oxy)-6-(methyloxy)quinazolin-4-amine.

来源网站：

中国工程科技知识中心

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