Endothelial nitric oxide synthase antagonists and uses thereof for inhibiting oxygen toxicity

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专利权人:

Dmitry Kondrikov;Yunchao Su

发明人:

Yunchao Su,Dmitry Kondrikov

申请号：

US13103667

公开号：

US08435947B2

申请日:

2011.05.09

申请国别(地区):

US

年份:

2013

代理人:

摘要：

Compositions and methods for inhibiting the interaction between eNOS and β-actin are provided for use in inhibiting or reducing lung injury from oxygen toxicity. One embodiment provides a synthetic or recombinant polypeptide having the β-actin binding domain of eNOS, wherein the polypeptide inhibits or reduces eNOS activity in lung endothelial cells.

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中国工程科技知识中心

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http://www.ckcest.cn/home/