GANYMED PHARMACEUTICALS GMBH;TRON - TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITÄTSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITÄT MAINZ GGMBH
发明人:
SAHIN, Ugur,TÜRECI, Özlem,WALTER, Korden,KREUZBERG, Maria,MITNACHT-KRAUS, Rita,LE GALL, Fabrice,JACOBS, Stefan
申请号:
SG11201708271T
公开号:
SG11201708271TA
申请日:
2016.04.13
申请国别(地区):
SG
年份:
2017
代理人:
摘要:
The present invention provides anti-CLDN18.2 antibody-drug conjugates which are effective for treating and/or preventing cancer diseases associated with cells expressing CLDN18.2, including gastric cancer, esophageal cancer, pancreatic cancer, lung cancer, ovarian cancer, colon cancer, hepatic cancer, head-neck cancer, and cancer of the gallbladder and metastases thereof.