HUANG, CHI YING,黄奇英,黃奇英,YANG, PAN CHYR,杨泮池,楊泮池,许照惠,許照惠,LEE, MENG HUA,李梦桦,李夢樺
申请号：
TW104128973
公开号：
TW201628624A
申请日:
2015.09.02
申请国别(地区):
TW
年份:
2016
代理人:
摘要：
The present invention relates to use of antipsychotic phenothiazine derivative for treatment of cancer. The invention also provides a use for manufacture a medicament, a pharmaceutical composition and a method for treating a cancer, and /or preventing or delaying cancer recurrence based on trifluoperazine. The invention further provides a use for manufacture a medicament, a pharmaceutical composition and a method for treating cancer based on thioridazine and its enantiomers. Additionally, the invention provides a use for manufacture a medicament, a pharmaceutical composition and a method for treating KRAS mutant NSCLC comprising thioridazine.本發明係關於一種抗精神病啡噻嗪衍生物用於治療癌症的用途。本發明亦依據三氟拉嗪來提供一種製造藥品的用途、一種醫藥組成物及一種治療癌症及/或預防或延遲癌症復發的方法。本發明進一步依據硫利達嗪及其鏡相異構物來提供一種製造藥品的用途、一種醫藥組成物及一種治療癌症的方法。此外,本發明提供一種製造藥品的用途、一種醫藥組成物及一種治療KRAS突變型NSCLC的方法,其係包含硫利達嗪。
