MODIFICATEURS ALLOSTÉRIQUES DE L'HÉMOGLOBINE AVEC UNE PARTIE LIBÉRANT DE L'OXYDE NITRIQUE

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专利权人:

Virginia Commonwealth University

发明人:

申请号：

EP14874450.1

公开号：

EP3092213A4

申请日:

2014.12.22

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

Allosteric hemoglobin (Hb) modifiers of hemoglobin which contain nitric oxide (NO) moieties allowing for the release of NO in vivo. The compounds retain the oxygen delivery capability of the allosteric hemoglobin modifier to bind Hb and enhance Hb's ability to deliver oxygen to cells and tissues, and also release NO from the NO moiety. Methods of delivering oxygen and/or NO to cells and tissues are also provided.

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