The Board of Trustees of the Leland Stanford Junior University
发明人:
申请号：
EP18775932.9
公开号：
EP3600323A1
申请日:
2018.03.30
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
Provided herein are compositions and methods for preventing or reversing T cell exhaustion. In particular, the present invention relates to methods of preventing or reversing T cell exhaustion by exposing T cells experiencing T cell exhaustion to particular tyrosine kinase inhibitors (e.g., dasatinib, ponatinib), or by expanding genetically engineered T cells in the presence of particular tyrosine kinase inhibitors (e.g., dasatinib, ponatinib).
