THE UNIVERSITY OF CHICAGO;THE BOARD OF REGENTS OF THE UNIVERSITY OF ILLINOIS
发明人:
Robert S. DAUM,Susan BOYLE-VAVRA,Michael E. JOHNSON
申请号：
US14776965
公开号：
US20160120852A1
申请日:
2014.03.14
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Compositions and methods are provided for treating or inhibiting a bacterial infection involving at least one antibiotic and a compound that potentiates the antibiotic activity of the antibiotic. In certain embodiments the antibiotic is a beta lactam. In further embodiments, the antibiotic is oxacillin. In additional embodiments, the potentiating compound is an inhibitor of vraSR operon expression. In specific embodiments, the bacterial infection involves an antibiotic-resistant bacteria.
