A non-reloadable surgical fastener cartridge is provided. The non-reloadable surgical fastener cartridge includes a cartridge body that includes a tissue contacting surface that includes a plurality of fastener retention slots. A plurality of surgical fasteners is disposed in the plurality of fastener retention slots. Each surgical fastener includes first and second legs of different lengths. A plurality of pushers is operably associated with the plurality of surgical fasteners. One or more of the pushers is configured such that, upon formation of a corresponding surgical fastener, a first area defined by the first leg is smaller than a second area defined by the second leg. The non-reloadable surgical fastener cartridge also includes an actuation mechanism operably associated with the plurality of pushers.
