Amy M. Elder;Francois Soucy;Sian Griffiths;Shomir Ghosh;Prakash Raman;Kevin Sprott;Qing Ye
发明人:
Shomir Ghosh,Prakash Raman,Kevin Sprott,Amy M. Elder,Sian Griffiths,Francois Soucy,Qing Ye
申请号:
US13281482
公开号:
US20120214807A1
申请日:
2011.10.26
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides compounds of general formula I:or a pharmaceutically acceptable salt thereof, wherein X, n, Y, and R1 are defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR2 and accordingly are useful for the treatment of a variety of inflammatory, allergic, and autoimmune diseases, disorders, or conditions.