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MITOGEN-ACTIVATED PROTEIN KINASE-DEPENDENT RECOMBINANT VACCINIA VIRUS (MD-RVV) AND USE THEREOF
专利权人:
发明人:
Takafumi Nakamura
申请号:
US15038145
公开号:
US20160281066A1
申请日:
2014.11.20
申请国别(地区):
US
年份:
2016
代理人:
摘要:
This invention provides a vaccinia virus that grows specifically in a cancer cell and damages such cancer cell and the use of such virus for treatment of cancer. Such mitogen-activated protein kinase-dependent vaccinia virus strain lacks functions of vaccinia virus growth factor (VGF) and O1L, it does not grow in normal cells but grows specifically in cancer cells, and it has oncolytic properties that specifically damage cancer cells.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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