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ПОДАВЛЕНИЕ РАКОВЫХ МЕТАСТАЗОВ
专利权人:
АКАДЕМИЯ СИНИКА (TW)
发明人:
ЛЯН Шу-Мэй (US),ЧИУ Чин-Фэн (TW),ХУН Шао-Вэнь (TW),ПЭН Цзэй-Мин (TW),ЛЯН Чи-Мин (US)
申请号:
RU2012125627/15
公开号:
RU2012125627A
申请日:
2010.11.19
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
1. A pharmaceutical composition for suppressing cancer metastasis in a subject comprising fibrillar protein and a pharmaceutically acceptable ekstsipient.2. A composition according to claim 1, wherein said fibrillary protein comprises fibrillar albumin.3. A composition according to claim 1, wherein said fibrillary protein comprises whey fibrillar albumin.4. A composition according to claim 1, wherein said fibrillary protein comprises fibrillar yaschura.5 virus capsid proteins. A composition comprising a therapeutically effective amount of the fibrillar human serum albumin and a pharmaceutically acceptable carrier, for use in treating mammalian patients cancer.6. The pharmaceutical composition of claim 5 wherein said cancer is characterized by overexpression of α5β1 integrin and / or αvβ3.7. A process for preparing a composition according to claim 3, comprising the steps of: obtaining a fibrillar human serum albumin ismeshivanie fibrillar human serum albumin in a therapeutically effective amount with pharmaceutically acceptable nositelem.8. A method according to claim 7 wherein the step of obtaining human serum albumin fibrillar further includes: dissolving human serum albumin in a detergent solution transmittance dissolved human serum albumin through the column for gel filtration with a pore size allowing to separate proteins with a molecular weight of 70 kDa and more elution with human serum albumin from kolonki.9. A method of treating cancer in a patient is a human, comprising administering to said patient a composition of 1.10. A method for treating cancer comprising administering nuzh1. Фармацевтическая композиция для подавления раковых метастазов у индивидуума, содержащая фибриллярный белок и фармацевтически приемлемый эксципиент.2. Композиция по п.1, где указанный фибриллярный белок содержит фибриллярный альбумин.3. Композиция по п.1, где указанный фибриллярный белок содержит фибриллярный сывороточный альбумин.4. Композиция по п.1, где указанный фибриллярный б
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