LI, CHIANG, JIA,LIU, JI-FENG,LI, YOUZHI,LI, WEI,ROGOFF, HARRY
申请号:
EP08829600
公开号:
EP2197878A4
申请日:
2008.09.05
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention relates to novel thiazole-substituted indolin-2-ones as inhibitors of CSCPK and related kinases; to methods of inhibiting cancer stem cells by using a kinase inhibitor; to pharmaceutical compositions containing such compounds; and to methods of using such compounds in the treatment of protein kinase related disorder in a mammal; and to processes of making such compounds and intermediates thereof.