Modified caspase-9 polypeptides and methods of use thereof

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专利权人:

Inc.;Allogene Therapeutics

发明人:

GALINDO CASAS, Meritxell,VAN BLARCOM, Thomas John

申请号：

AU2018359532

公开号：

AU2018359532A1

申请日:

2018.10.31

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

Provided herein are modified caspase-9 polypeptides, and chimeric caspase-9 proteins containing the modified caspase-9 polypeptides. The disclosure further provides polynucleotides encoding these proteins, engineered host cells containing these polynucleotides and proteins, including host cells that co-express a chimeric antigen receptor, and methods of making and using the same.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/