BEHAN, Dominic P.,GLICKLICH, Alan,GROTTICK, Andrew J.,KAM, Maria Matilde Sanchez,SHANAHAN, William R.
申请号：
USUS2015/058016
公开号：
WO2016/069875A1
申请日:
2015.10.29
申请国别(地区):
WO
年份:
2016
代理人:
摘要：
Provided are compositions comprising (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine or a pharmaceutically acceptable salt, solvate, or hydrate thereof, optionally in combination with a supplemental agent, and methods for reducing the frequency of smoking tobacco in an individual attempting to reduce frequency of smoking tobacco aiding in the cessation or lessening of use of a tobacco product in an individual attempting to cease or lessen use of a tobacco product aiding in smoking cessation and preventing associated weight gain controlling weight gain associated with smoking cessation by an individual attempting to cease smoking tobacco reducing weight gain associated with smoking cessation by an individual attempting to cease smoking tobacco treating nicotine dependency, addiction and/or withdrawal in an individual attempting to treat nicotine dependency, addiction and/or withdrawal or reducing the likelihood of relapse use of nicotine by an individual attempting to cease nicotine use comprising administering (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine or a pharmaceutically acceptable salt, solvate, or hydrate thereof, optionally in combination with a supplemental agent.Linvention concerne des compositions comprenant de la (R)-8-chloro-1-méthyl-2,3,4,5-tétrahydro-1H-3-benzazépine ou un sel, solvate ou hydrate pharmaceutiquement acceptable de celle-ci, éventuellement en association avec un agent supplémentaire, et des procédés pour : réduire la fréquence de consommation de tabac chez un individu essayant de diminuer sa consommation de tabac aider à cesser ou réduire la consommation dun produit du tabac chez un individu essayant de cesser ou de diminuer sa consommation dun produit du tabac aider au renoncement au tabac et prévenir la prise de poids associée lutter contre la prise de poids associée au renoncement au tabac par un individu essayant de renoncer au tabac réduire la prise de poids associée au renoncement au tabac par un individu
