נוגדנים הנקשרים ל p4d12191, תכשירים המכילים אותם ושימושים בהם

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专利权人:

SEATTLE GENETICS INC.;AGENSYS INC.

发明人:

申请号：

IL22546013

公开号：

IL225460A

申请日:

2013.03.24

申请国别(地区):

IL

年份:

2018

代理人:

摘要：

The present disclosure relates to antibody drug conjugates (ADC's) with auristatin E that binds to 191P4D12 protein and variants thereof. 191P4D12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in some cancers. The ADC's of provide a therapeutic composition for the treatment of cancer.

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